1Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan; 2Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; 3Department of Computer Science and Information Engineering, National Cheng-Kung University, Tainan, Taiwan
Brain iron accumulation may be related to various neurological diseases such as Parkinsons disease, Alzheimers disease, and multiple sclerosis. Quantitative MR techniques, such as MR relaxometry and susceptibility mapping can be helpful toward quantifying brain iron content. A novel approach is proposed that can simultaneously measure T2, T2* and susceptibility-induced internal field perturbations from the same rapid scan. It is hoped that the present method may prove a useful tool toward investigating conditions linked with elevated brain iron content.