Peter T. Fwu1, 2, Jeon-Hor Chen3, Yuting Lin1, Wei-Ching Lin4, Po-Jung Tseng1, Eddie Lin1, Min-Ying Su1, 2
1Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, CA, United States; 2Department of Physics and Astronomy, University of California, Irvine, CA, United States; 3Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California Irvine, Irvine, CA, United States; 4Department of Radiology, China Medical University Hospital, Taichung, Taiwan
Regional hypothermia through endorectal cooling balloon (ECB) is shown capable of minimizing the long term urinary incontinence and sexual dysfunction. However, there is no tool to optimize ECB setting to reach the desired protective cooling effect. A bioheat simulation equation based on each individual patients own 3D anatomy is developed to model the cooling process by using the finite element method. Using this model, we evaluated the impact of geometrical distance from ECB, the balloon temperature, and the presence of blood. In addition, the effect of arterial ligation to decrease the blood perfusion to NBV was also evaluated.