Harald Kramer1, Elisabeth Arnoldi1, Christopher J. Francois2, Andrew L. Wentland3, Konstantin Nikolaou1, Bernd J. Wintersperger4, Maximilian F. Reiser1, Thomas M. Grist2
1Institute for Clinical Radiology, Ludwig-Maximilians-University Munich, Munich, Bavaria, Germany; 2Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States; 3Department of Radiology, University of Wisconsin - Madison, Madison, WI, United States; 4Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada
Several different contrast agents exist for MRI and Despite the fact these are all Gadolinium (Gd) based, they feature different characteristics. We performed static and dynamic MRA of the Carotid arteries with 3 different agents at single dose at 3.0T. Qualitative image quality as well as SNR, CNR and vessel sharpness was assessed. At equimolar doses 1.0 molar Gadobutrol demonstrates superior SNR / CNR to Gadobenate dimeglumine and Gadoterate meglumine with subjectively higher image quality in static and dynamic Carotid MRA. The decreased injected volume with Gadobutrol does not result in significantly different edge blurring of vessels.