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Abstract #0184

Noninvasive assessment of myocardial fibrosis using Cardiovascular Magnetic Resonance (CMR) T1rho-mapping techniques in End-Stage Renal Disease (ESRD) hemodialysis patients

Lin Wang 1 , Shijun Zhang 1 , Yixiang Wang 2 , and Shenghong Ju 1

1 Radiology, Zhongda Hospital, Nanjing, Jiangsu, China, 2 Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong, China

Autopsy studies demontstrated that the typical pathologic characteristic of the myocardium of End-Stage Renal Disease (ESRD) hemodialysis patients was left ventricular hypertrophy (LVH) and diffused collagen and fibrosis deposition in extracellular matrix. Due to the contraindication of the contrast medium of this kind of patients, the myocardial fibrosis is hardly evaluated with current modalities. The purpose of this study was to determine whether T1rho imaging can be used as a noninvasive method with no contrast enhancement to detect myocardial fibrosis in ESRD maintained on hemodialysis patients.

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