Characterizing white matter pathways of the living rat brain by Tractometry
Daniel Barazany 1,2 , Silvia De Santis 1,2 , Mara Cercignani 3 , Yaniv Assaf 2 , and Derek K Jones 1
School of Psychology, Cardiff University,
Cardiff, United Kingdom,
of Neurobiology, Tel Aviv University, Tel Aviv, Israel,
Imaging Sciences Centre, Brighton and Sussex Medical
School, Falmer, East Sussex, United Kingdom
Tractometry framework aims to establish more accurate
and informative description of white matter brain tissue
by on exploiting imaging methods which provide higher
sensitivity to the underlying tissue subcomponents such
as the composite hindered and restricted model of
diffusion (CHARMED) and qMT. In this work we utilized
tractometry microstructural metrics to examine and
characterize two different white matter pathways of the
living rat brain, the corpus callosum and the fimbria.
We show the high sensitivity of these metrics to
differentiate between the two fibers.
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