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Abstract #0325

Accelerating MR Elastography with Sparse Sampling and Low-Rank Reconstruction

Curtis L Johnson 1 , Joseph L Holtrop 1,2 , Anthony G Christodoulou 1,3 , Matthew DJ McGarry 4 , John B Weaver 4,5 , Keith D Paulsen 4,5 , Zhi-Pei Liang 1,3 , John G Georgiadis 1,6 , and Bradley P Sutton 1,2

1 Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2 Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 3 Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 4 Thayer School of Engineering, Dartmouth College, Hanover, NH, United States, 5 Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States, 6 Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States

Magnetic resonance elastography (MRE) requires the acquisition of a large number of images with differing gradient encoding direction, polarity, and displacement phase offsets. However, these images share a lot of information and can be represented through a reduced model order. In this work we demonstrate the ability to accelerate brain MRE acquisitions through sparse sampling and low-rank image reconstruction. Reducing the reconstructed model order from 48 to 10 resulted in virtually unchanged mechanical properties, and allowed for undersampling by factors up to 4x.

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