Abstract #0331
Accelerated MPIO-Labeled Cell Imaging in the Heart
Anthony G. Christodoulou 1 , T. Kevin Hitchens 2 , Yijen L. Wu 2 , Zhi-Pei Liang 1 , and Chien Ho 2
1
Department of Electrical and Computer
Engineering, University of Illinois at Urbana-Champaign,
Urbana, IL, United States,
2
Pittsburgh
NMR Center for Biomedical Research, Department of
Biological Sciences, Carnegie Mellon University,
Pittsburgh, PA, United States
Low-rank (subspace) imaging with temporal navigation and
sparse sampling of (k, t)-space has previously been used
to accelerate several cardiac imaging applications. Here
we describe a more efficient self-navigated pulse
sequence to acquire both navigator and sparse data in a
single TR, doubling imaging speed to approach 100 frames
per second. We demonstrate the assessment of myocardial
inflammation in rats through self-navigated T2*-weighted
imaging of immune cells labeled with micron-sized
paramagnetic iron oxide (MPIO) particles.
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