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Abstract #0338

The Phase and Magnetization Transfer Characteristics of a Novel Myelin Water Imaging Method (ViSTa)

Hyo Min Lee 1,2 , Daeun Kim 1 , Sung Suk Oh 1 , Joon Yul Choi 1 , Se-Hong Oh 1 , and Jongho Lee 1

1 Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2 Bioengineering, University of Pennsylvania, Philadelphia, PA, United States

The signal characteristics of a novel myelin water imaging method, direct visualization of short transverse relaxation time component (ViSTa), have been explored. The results show that the phase evolution and magnetization transfer effects of ViSTa match well with those of myelin water and are substantially different from those of GRE. These results, in addition to short T2* characteristics of ViSTa, further support the origin of ViSTa signal to myelin water.

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