Amide Proton Transfer and 3D Pseudo-continuous Arterial Spin Labeling MRI in Grading Cerebral Gliomas
Meiyun Wang 1 , Yan Bai 1 , Panli Zuo 2 , Benjamin Schmitt 3 , Dapeng Shi 1 , Jie Tian 4 , and Jinyuan Zhou 5
Department of Radiology, Henan Provincial
Peopls's Hospital, Zhengzhou, Henan, China,
Healthcare, Beijing, China,
of Automation, Chinese Academy of Sciences, Beijing,
of Radiology, Johns Hopkins University, Baltimore, MD,
This study investigated the value of amide proton
transfer (APT) and 3D pseudo-continuous arterial spin
labeling (pCASL) MRI in grading gliomas. The results
showed a positive correlation between endogenous mobile
proteins and CBF in gliomas and suggested that the
parameters derived from APT and 3D pCASL MRI are useful
in grading cerebral gliomas.
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