Regional Frank-Starling relations in infarcted swine via dynamic real-time MRI
Francisco Contijoch 1 , Walter RT Witschey 1 , Jeremy McGarvey 1 , Madonna Lee 1 , Norihiro Kondo 1 , Toru Shimaoka 1 , Chikashi Aoki 1 , Satoshi Takebayashi 1 , Gerald A Zsido 1 , Christen Dillard 1 , Joseph H Gorman 1 , Robert C Gorman 1 , and James J Pilla 1
University of Pennsylvania, Philadelphia,
PA, United States
Current imaging methods provide non-invasive and high
spatial resolution approach, but are load-dependent
since values obtained are influenced by the
end-diastolic volume (preload) and arterial impedance (afterload).
In this work, we developed an MRI method to quantify
regional response to alterations in preload. As a
result, we obtain regional Frank-Starling relations in
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