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Abstract #0451

Intravoxel Incoherent Motion Imaging of Renal Tumors: Subtype Differentiation Using Voxel-based Histogram Analysis

Byron Gaing 1 , Eric Edward Sigmund 1 , William Huang 2 , James Babb 1 , David Stoffel 1 , and Hersh Chandarana 1

1 Radiology, NYU Langone Medical Center, New York, New York, United States, 2 Urology, NYU Langone Medical Center, New York, United States

Renal cell carcinomas are a heterogeneous group of tumors not only with their varying biologic behavior but also in their response to targeted therapies. Previous work has shown that IVIM parameters are useful in differentiating common subtypes of RCC based on whole ROI analysis. Our results confirm previous work showing a clear trend separating more vascular (clear cell) from less vascular (papillary) tumor subtypes using the IVIM metric fp. Additionally, our initial results suggest differentiation between benign and malignant subtypes of renal tumors may also be possible. These findings could potentially impact surgical planning.

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