Compression Effects in Breast MR Elastography
Jun Chen 1 , Kathleen Brandt 1 , Karthik Ghosh 1 , Roger Grimm 1 , Kevin Glaser 1 , Jennifer Kugel 1 , Kay Pepin 1 , and Richard Ehman 1
Mayo Clinic, Rochester, MN, United States
In conventional breast MR Elastography (MRE), the driver
compresses the breasts to maintain mechanical coupling
for wave transmission. This compression could introduce
a significant bias into the measured stiffness of breast
tissue. For the first time, this study reports strong
evidence of breast compression effects in breast MRE.
With 20% breast compression, glandular and adipose
tissue stiffness increased by 53.8% and 103.8%
respectively. Therefore, true breast tissue stiffness
can be measured only when there is no compression, such
as when using the noncompressive breast MRE technique
utilized in this study.
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