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Abstract #0730

Anisotropic Power Maps: A diffusion contrast to reveal low anisotropy tissues from HARDI data.

Flavio Dell'Acqua 1,2 , Luis Lacerda 1 , Marco Catani 3 , and Andrew Simmons 1,2

1 Dept of Neuroimaging, King's College London, Institute of Psychiatry, London, United Kingdom, 2 NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia, King's College London, Institute of Psychiatry, London, United Kingdom, 3 Dept of Forensics and Neurodevelopmental Sciences, King's College London, Institute of Psychiatry, London, United Kingdom

All the anisotropy information in a HARDI signal is captured by the spherical harmonic coefficients of even order l ≥ 2. By measuring the total power of these coefficients it is possible to obtain an absolute measure of how much anisotropy information is available in each HARDI signal or a measure of the total anisotropic power (AP). This index can be use to better quantify and discriminate low anisotropy regions from CSF regions or noise. This measure is entirely model independent, robust to noise and can be easily applied on a large number of existing datasets.

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