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Abstract #0750

Regional Differences in the 7T BOLD-CVR Response to Ramped Hypercapnic Stimulus Suggest Pressure/Flow dependent Signal Properties

Alex Bhogal 1 , Marielle Philippens 2 , Jeroen C.W. Siero 1 , Esben Petersen 1 , Joe Fisher 3 , Peter Luijten 1 , and Hans Hoogduin 1

1 Radiology, University Medical Center, Utrecht, Netherlands, 2 Radiotherapy, University Medical Center, Utrecht, Netherlands, 3 Anaesthesia & Physiology, University Health Network, Toronto, Ontario, Canada

Here we examine differences in the cerebrovascular reactivity (CVR) response of gray and white matter to a progressive hypercapnic stimulus. Tissue-specific differences arise which cannot be explained by CVR response delay alone.

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