Increase in SNR of 370 % for 31P MR spectroscopy by adiabatic multi-echo polarization transfer and adiabatic multi-echo direct detection in one repetition time
Wybe JM van der Kemp 1 , Vincent O Boer 1 , Peter R Luijten 1 , and Dennis WJ Klomp 1
Radiology, UMC Utrecht, Utrecht, Netherlands
The SNR per time unit of the signals of heteronuclear
J-coupled 31P metabolites can be increased by using an
adiabatic multi-echo polarization transfer technique
with an even number of 180 refocusing pulses on the 31P
channel combined with an adiabatic multi-echo direct
detection sequence in one TR, without adversely
affecting the polarization transfer or the direct
detection signal. The in vivo increase in SNR for
phosphomonoesters as compared to low flip Ernst angle
excitation pulse acquire can be up to 370%.
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