Abstract #0954
Enhanced detection of cortical lesions in multiple sclerosis using magnetization transfer and double inversion recovery
Refaat E Gabr 1 and Ponnada A Narayana 1
1
Diagnostic and Interventional Radiology,
University of Texas Health Science Center at Houston,
Houston, TX, United States
Double inversion recovery (DIR) is a powerful imaging
technique for detecting cortical lesions in multiple
sclerosis. Yet, the number of lesions detected by DIR is
significantly lower than number of lesions identified on
histology. Here we propose using magnetization transfer
to enhance the suppression of white matter to improve
the depiction of cortical lesions. Experiments on 14
patients show that magnetization transfer DIR (MT-DIR)
doubles the number of detected lesions and improves the
lesion contrast by ~30%.
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