Comparison of the value of DWI based on monoexponential and stretched exponential model in differential diagnosis between benign and malignant lesions of breast
Jie He 1 , Yan Zhang 1 , Jingliang Cheng 1 , Ying Hu 1 , Anfei Wang 1 , Dandan Zheng 2 , and Xiaoyan Wang 1
Department of MRI, the First Affiliated
Hospital of Zhengzhou University, Zhengzhou, HeNan,
healthcare, Beijing, China
MRI has been widely used in the diagnosis of breast
disease. However, the calculation of apparent diffusion
coefficient by simple monoexponential relationship
between MRI signal and b value does not fully account
for tissue behavior. Intravoxel incoherent motion (IVIM)
method allows quantitative parameters that reflect
tissue micro capillary perfusion and tissue diffusivity.
In this study, the stretched-exponential model was used
to generate and distributed diffusion coefficient (DDC)
maps. The values and DDCs were compared with
traditional monoexponential ADC in the differential
diagnosis of breast benign and malignant lesions.
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