Is the reaction-diffusion equation an accurate model of C6 glioma growth?
David A. Hormuth, II 1,2 , Jared A. Weis 2 , and Thomas E. Yankeelov 2
Biomedical Engineering, Vanderbilt
University, Nashville, TN, United States,
of Imaging Science, Vanderbilt University, Nashville,
TN, United States
The reaction-diffusion equation is a common model used
to describe tumor growth. Quantitative imaging
measurements may be used to drive this model. Using
simulated tumor growths and experimentally measured
tumor growths, we determined the acquisition strategies
necessary to allow for accurate estimate of model
parameters. Additionally, the accuracy of this model in
predicting in vivo tumor growth is tested. The accuracy
of predicted and observed growths are compared between
the simulated and experimental datasets.
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