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Abstract #1199

In vitro micro-imaging investigation of osteoporotic and osteoarthritis femoral specimens by means of internal magnetic field gradient (IMFG)

Giulia Di Pietro 1,2 , Eleonora Piccirilli 3 , Monica Celi 3 , Umberto Tarantino 3 , and Silvia Capuani 2,4

1 IIT@Sapienza, Physics Department, Sapienza University, Rome, Rome, Italy, 2 Physics Department, Sapienza University, Rome, Rome, Italy, 3 Department of Orthopaedics and Traumatology, University of Rome Tor Vergata, Rome, Rome, Italy, 4 CNR IPCF UOS Roma, Physics Department, Sapienza University, Rome, Italy

In this in vitro study performed at 9.4T, the internal magnetic field gradient (IMFG) was used to discriminate between femoral neck samples extracted from osteoporotic (OP) and osteoarthritic (OA) patients. IMFG values were lower in OP compared to OA suggesting a higher trabecular density in OA specimens. IMFG values were lower in the metaphysis compared to subchondral section in both OP and OA samples. These results are in agreement with the packing of subchondral bone occurring in OA. In subchondral section of OP specimens the higher IMFG values are due to the marrow fat content increase

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