A novel MR compatible indentation setup to study the etiology of pressure ulcers and related deep tissue injury.
Jules L. Nelissen 1 , Willeke A. Traa 2 , Larry A. de Graaf 1 , Kevin M. Moerman 3 , Aart J. Nederveen 3 , Cees W. Oomens 2 , Klaas Nicolay 1 , and Gustav J. Strijkers 1
Biomedical NMR, Department of Biomedical
Engineering, Eindhoven University of Technology,
Tissue Biomechanics and Engineering, Department of
Biomedical Engineering, Eindhoven University of
Technology, Eindhoven, Netherlands,
of Radiology, Amsterdam Academic Medical Center,
A novel MR compatible indentor was designed, build and
tested to provide new insights in the etiology of
pressure ulcer related deep tissue injury. The design
allows flexible positioning of the indentor and was
tested by applying 2h sustained mechanical loading to
the tibialis anterior (TA) muscle of rat inside a MR
scanner. T2 weighted scans, T2 maps and angiography were
used to assess skeletal muscle injury and physiological
changes. Hyperenhancement due to the formation of edema,
resembling the structure of vasculature in the TA muscle
is observed in strong T2weighted scans. T2 maps show the
similar capillary bed structure.
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