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Abstract #1227

A BOLD effect on different calf muscle groups in elderly females

Chenfei Ye 1 , James F. Griffith 2 , Heather T. Ma 1 , David K. Yeung 2 , Alvin F. Li 2 , and Xu Xing 1

1 Department of Electronic and Information Engineering, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen, Guangdong, China, 2 Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong

This study examined the BOLD effect on calf muscles in elderly subjects to investigate the oxygenation characteristics in different calf muscle groups for the elderly females. Temporary vascular occlusion was induced with air-cuff compression of the thigh and BOLD-MRI data curve was fitted to derive quantitative parameters. The BOLD signal in soleus muscle showed the lowest minimum ischemic value during ischemia and the steepest slope during hyperemia. As soleus muscle is mainly composed by slow-twitch oxidative muscle fibers, current results may be due to a higher vascular bed density and better endothelial function in such muscle.

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