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Abstract #1252

MRI signal texture parameters within human intervertebral discs as biomarkers of spine pathologies and severities

Delphine Perie 1,2 , Clemence Balosetti 1,2 , Sofiane Achiche 1 , and Hubert Labelle 2

1 Mechanical Engineering, Ecole Polytechnique de Montral, Montreal, QC, Canada, 2 Research Center, CHU Sainte Justine, Montreal, QC, Canada

In both scoliosis and spondylolisthesis, the progression of the spine deformation leads to the degeneration of intervertebral discs characterized by a change in its structure and biochemical composition. The MRI images of 79 patients (32 with scoliosis, 32 with spondylolisthesis and 15 with herniated discs) were analysed using texture parameters extracted from the intensity histograms of the grey level, contrast, correlation, energy and homogeneity images. The results validated our hypothesis: the calculated tissue-specific texture features can effectively discriminate the pathologies and some of their severities. This method has the advantage of supporting the interesting possibility of developing robust non-invasive predictive methods for the diagnosis of the severities of spine pathologies.

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