En Route to Probing Human Myocardial Microstructure in vivo Using Susceptibility Based MRI at 7.0 T
Till Huelnhagen 1 , Fabian Hezel 1 , and Thoralf Niendorf 1,2
Berlin Ultrahigh Field Facility (B.U.F.F.),
Max Delbrueck Center for Molecular Medicine, Berlin,
and Clinical Research Center, a joint cooperation
between the Charite Medical Faculty and the Max
Delbrueck Center, Berlin, Germany
The complex microstructure of the myocardium is pivotal
for cardiac function and can provide important
information about the underlying (bio)physical
principles and (patho)physiological mechanisms. Probing
human myocardial fiber structure in vivo has been
described, but remains challenging due to cardiac and
respiratory motion. Susceptibility based MRI provides
excellent contrast which can be used to investigate
tissue microstructure and track fibers in the brain.
Recognizing this opportunity the work explores the
applicability of susceptibility weighted MRI for probing
human myocardial microstructure in vivo at 7.0 T.
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