High-Resolution Perfusion-Weighted Imaging without Tagging Pulses

In this abstract, a novel isotropic perfusion-weighting approach is proposed, where bi-polar gradients are used instead of the tagging pulses to obtain a high-resolution PW image with radial trajectory. By using a pair of spin-echo (SE) images acquired with single and double bi-polar gradients from multi-directions, anisotropic characteristics of the cerebral perfusion are also considered. Computer simulations were performed to evaluate the relation between the proposed method and the cerebral perfusion. MR experiment results from in-vivo brain imaging show that the proposed method produces a high-resolution PW image.

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