Magnetic Resonance Rheology of the human brain
Sebastian Theilenberg 1 , Jakob Bindl 1 , Anna-Lisa Kofahl 1 , Deniz Ulucay 1 , Judith Wild 1 , Alexandra Vohlen 1 , Sylvia Napiletzki 1 , Jrgen Finsterbusch 2 , Bernd Weber 3 , Carsten Urbach 1 , and Karl Maier 1
HISKP, University of Bonn, Bonn, Germany,
Medical Center Hamburg-Eppendorf, Hamburg, Germany,
& Brain GmbH, Bonn, Germany
Magnetic Resonance Rheology is a novel method to image
the viscoelastic properties of tissue in vivo using MRI
phase images. By introducing a free fall over a small
height the steady state of the brain tissue is
disturbed, causing the tissue to move relative to the
cranial bone. The exact trajectory of this motion is
dependent on the local viscoelastic properties.
Measuring these using a motion sensitive single-shot EPI
sequence synchronized to the free fall creates a phase
contrast. By varying the point in time of measurement
the whole trajectory can be investigated.
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