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Abstract #1693

Remotely induced cerebral strain for enhanced safety and acceptance of MR elastography of the brain

Andreas Fehlner 1 , Sebastian Papazoglou 1 , Jing Guo 1 , Kaspar-Josche Streitberger 1 , Sebastian Hirsch 1 , Jrgen Braun 2 , and Ingolf Sack 1

1 Department of Radiology, Charit - Universittsmedizin Berlin, Berlin, Germany, 2 Institute of Medical Informatics, Charit - Universittsmedizin Berlin, Berlin, Germany

A new driver for brain MRE is introduced which avoids the direct application of vibrations to the head without compromising sufficiently high extrinsic wave amplitudes needed for MRE. Waves are introduced into the cranial cavity by a chest cradle mounted to a piezo-based actuator which was placed at the end of the patient table. The new driver is particularly suited for low drive frequencies (2540 Hz) which are capable to resolve anatomical details and provide viscoelastic parameters in agreement to previous work. The new method is demonstrated in ten healthy volunteers for 8 driving frequencies and two 3D views.

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