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Abstract #1724

Phase sensitive inversion recovery imaging of the spinal cord in clinical scan times

Nico Papinutto 1 , Valentina Panara 1,2 , Sinyeob Ahn 3 , Kevin Johnson 3 , Regina Schlaeger 1,4 , Eduardo Caverzasi 1 , William Stern 1 , Bruce Cree 1 , Stephen Hauser 1 , and Roland G Henry 1

1 Dept. of Neurology, UCSF, San Francisco, CA, United States, 2 ITAB - Institute of Advanced Biomedical Technologies, University "G. D'Annunzio", Chieti, Italy, 3 Siemens Healthcare USA, San Francisco, CA, United States, 4 Dept. of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland

In this study we present two spinal cord Phase Sensitive Inversion Recovery (PSIR) imaging protocols that candidate to be implemented in clinical Multiple Sclerosis centers. We optimized a 2D and a 3D version of the same protocol that show great canal/cord, grey matter/white matter and lesion/cord contrasts, retaining a good in plane resolution and short acquisition time. First we show how these protocols provide consistent and reproducible cord and grey matter area measurement. Second we show how the 3D version of the protocol provides a very reliable detection and localization of MS lesions. The short scan time makes the two proposed protocols very interesting for clinical environments.

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