Early high b-value diffusion MRI of the preterm infant brain highlights radial organisation of the developing cortex
Kerstin Pannek 1 , Joanne George 1 , Paul Colditz 1 , Roslyn Boyd 1 , and Stephen Rose 2
The University of Queensland, Brisbane,
Australian E-Health Research Centre, CSIRO, Brisbane,
Diffusion MRI is a promising tool for assessing brain
maturation in preterm infants. In preterm infants
scanned between 30 to 33 weeks postmenstrual age, we
investigated the impact of the diffusion acquisition
scheme on the resulting diffusion measures. A higher
b-value led to increases in diffusion anisotropy in
cortical grey matter, while anisotropy remained largely
unchanged in white matter. High b-value diffusion MRI
may provide unique insights into cortical development in
prematurely born infants.
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