Atypical language lateralization in adult temporal lobe epilepsy patients: fMRI study using statistical threshold and spatial masking
Steve H Fung 1,2 , Christof Karmonik 1,2 , Mario F Dulay 1,2 , Robert G Grossman 1,2 , and Amit Verma 1,2
Houston Methodist Research Institute,
Houston, Texas, United States,
Methodist Hospital, Houston, Texas, United States
We investigated the effect of statistical threshold and
various spatial masks on laterality index (LI)
calculation in determining language lateralization in
patients with temporal lobe epilepsy (TLE) evaluated
using fMRI with language tasks. Majority of patients
with TLE had some atypical lateralization, suggesting
possible plasticity/reorganization of language function
in patients with TLE.
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