Abstract #1981
COMPARISON OF NAA DYNAMICS IN TASK-ACTIVATED MOTOR CORTEX IN THE NORM AND SCHIZOPHRENIA
Natalia Semenova 1,2 , Dmitry Kupriyanov 3 , Maxim Ublinskiy 1 , Irina Lebedeva 4 , and Tolibjon Akhadov 1
1
Children Emergency Surgery and Trauma
Institute, Moscow, Russian Federation,
2
N.M.Emanuel
Institute of Biochemical Physics, Russian Academy of
Sciences, Moscow, Russian Federation,
3
Philips
Healthcare, Moscow, Russian Federation,
4
Mental
Health Research Center of Russian Academy of Medical
Sciences, Moscow, Russian Federation
The aim of this study was the analysis of motor cortex
metabolism dynamics during period of BOLD response to
fMRI motion task. The BOLD signal demonstrated maximum
at the 6th sec after target stimulus for both patient
and control groups, with lower intensity for
schizophrenia patients. For control group, NAA decreased
at the 12th second after fMRI motion task presentation
and recovered to the initial value at the 15th second.
Patient group demonstrates different dynamics of NAA in
motor cortex with smaller NAA intensity changes.
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