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Abstract #1996

Reduced Spontaneous Neural Activity in psychogenic Erectile Dysfunction:A Resting-State Functional Magnetic Resonance Imaging Study.

Min Guan 1 , Minghao Dong 2 , Xiangsheng Zhang 3 , Wei Qin 2 , Meiyun Wang 1 , Dapeng Shi 1 , and Jie Tian 2

1 Radiology, People's Hospital of Zhengzhou University, ZhengZhou, HeNan, China, 2 School of Life Science and Technology of XiDian University, Shannxi, China, 3 Urology, People's Hospital of Zhengzhou University, HeNan, China

Psychogenic ED has a high prevalance and a significant impact on the quality of life of sufferers and their partners.Little is known about the central pathological mechanism of psychogenic ED patients. Resting-state functional MR imaging and the Regional homogeneity (ReHo) method has been successfully used to investigate the functional modulations in patients with phychiatric diseases. We investigated neural activity in the resting state of psychogenic ED using ReHo method.Our present study for the first time demonstrated psychogenic ED exhibited decreased ReHo in the left VMPFC and right hippocampus, may leading to further improvement of the understanding of the pathogenetic mechanism.

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