Abstract #2000
White Matter Impairment in Depression and Hypertension: A Diffusion Kurtosis Imaging Study at 3-T MR
Xiangzhu Zeng 1 , Huishu Yuan 1 , Ying Liu 1 , Zheng Wang 1 , and Han Zhang 2
1
Dept of Radiology, Peking University Third
Hospital, Beijing, Beijing, China,
2
Dept
of the consultation liaison, Peking University Mental
Health Institute, Beijing, Beijing, China
As a new diagnostic tool for cerebral microstructure
impairment, Diffusion Kurtosis imaging (DKI) has the
ability to assess the white matter impairment of tissues
by investigating water diffusion with a non-Gaussian
model. Mean kurtosis(MK) is a key parameters of DKI and
reveals the white matter damage accurately. This work
evaluates the diagnostic utilities of MK in the case of
depression and hypertension and specifies the white
matter impairment in these patients.
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