Seemingly Inconsistency between Damaged White Matter Structure and Increased Functional Connectivity in Cingulum: Initial Response of Brain Plasticity to Trauma
Armin Iraji 1 , Hamid Soltanian-Zadeh 2 , Randall Benson 1 , E. Mark Haacke 1 , and Zhifeng Kou 3
Wayne State University, DETROIT, MI, United
of Tehran, Tehran, Iran,
State University, Detroit, Michigan, United States
Detection of the neuropathological or physiological
substrates may hold the best opportunity to improve the
diagnosis and proactive treatment of mTBI patients.
Functional and structural connectivities can be a good
index to investigate the effect of brain injury. The
posterior cingulate cortex is renowned as the brains
central hub, which integrates and relays the
information; therefore, it involves many brain
functional networks and regulates their activation based
on information that it gathers from the entire central
nervous system (CNS). We examine the change in the PCC
connectivity using both resting state fMRI and
probabilistic diffusion tractography.
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