Abstract #2154
Accuracy of Hepatic Fibrosis Staging Using T2-WI and Texture Analysis
Karen Buch 1 , Baojun Li 2 , Hei Shun Yu 2 , Brian Tischler 3 , Naznin Daginawala 3 , and Stephan Anderson 4
1
Radiology, Boston University Medical Center,
Boston, MA, United States,
2
Boston
University Medical Center, Boston, United States,
3
Boston
University Medical Center, MA, United States,
4
Radiology,
Boston University Medical Center, Boston, United States
The purpose of this study was to evaluate the accuracy
of texture analysis applied to T2-weighted images to
assess hepatic fibrosis using a linear discriminant
analysis. A total of 27 patients with varying grades of
biopsy-proven hepatic fibrosis were analyzed with a
sensitivity of up to 90% and specificity of 88% for GLCM
entropy versus energy texture parameters. The
development of accurate, non-invasive methods for the
assessment and staging of liver fibrosis is crucial
given a growing global impact of chronic liver disease
and fibrosis. The application of texture analysis tools
using T2-weighted images, possibly as part of a
multi-parametric approach, affords the possibility of
developing an accurate, noninvasive assessment of
hepatic fibrosis.
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