T1 relaxation of the liver; a new biochemical marker of liver function in patients with diffuse liver disease
Yukihisa Takayama 1 , Akihiro Nishie 2 , Yoshiki Asayama 2 , Yasuhiro Ushijima 2 , Nobuhiro Fujita 2 , Koichiro Morita 2 , Takashi Yoshiura 2 , Tomoyuki Okuaki 3 , Makoto Obara 3 , and Hiroshi Honda 2
Department of Molecular Imaging and
Diagnosis, Graduate School of Medical Sciences, Kyushu
University, Fukuoka, Japan,
of Clinical Radiology, Graduate School of Medical
Sciences, Kyushu University, Fukuoka, Japan,
Electronics Japan, Tokyo, Japan
We investigated the clinical utility of T1
for the assessment of liver function in patients with
chronic liver diseases (CLD) by comparing T1
with patientsf blood serum parameters. T1
of the liver parenchyma showed significant correlations
with serum albumin level, serum total and direct
bilirubin levels, and ICG-R15 (the retention rate of
indocyanine green 15 min after administration).
of the liver parenchyma were prolonged with increasing
ICG-R15 which indicates a worsening of liver function.
may server as a new biochemical marker of liver
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