Abstract #2161
T1 mapping on gadoxetate disodium enhanced MRI in patients with primary sclerosing cholangitis (PSC)
Kristina Imeen Ringe 1 , Marcel Gutberlet 1 , Frank Wacker 1 , and Hans-Jrgen Raatschen 1
1
Department of Diagnostic and Interventional
Radiology, Hannover Medical School, Hannover, Germany
In our prospective study we sought to assess the value
of T1-mapping of the liver on gadoxetate-disodium
enhanced MRI in patients with PSC. In 40 patients
T1-mapping of the whole liver was performed using a 3D
GRE-sequence with different flip angles before and after
contrast injection. T1 relaxation times in all liver
segments were assessed and correlated with liver
function tests. T1 relaxation times after contrast
injection significantly decreased and correlated with
bilirubin, cholinesterase and GOT. Our findings may be
useful for dynamic evaluation and follow-up of patients
with PSC, as well as for guidance of biopsies.
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