Renal Perfusion Imaging with Pseudo-continuous Arterial-Spin Labelling (pCASL) at 3.0T: Repeatability in Healthy volunteers.
Magdalena Sokolska 1 , David Thomas 2 , Alan Bainbridge 1 , Xavier Golay 2 , Stuart Taylor 3 , Shonit Punwani 3 , and Douglas Pendse 3
UCH Medical Physics and Bioengineering,
London, London, United Kingdom,
Institute of Neurology, London, London, United Kingdom,
for Medical Imaging, UCL, London, United Kingdom
Renal diseases are associated with abnormalities in
renal perfusion. Furthermore, characterisation of focal
renal lesions such as carcinomas is dependent on the
assessment of renal vascularity. Traditionally renal
perfusion imaging has relied on contrast agents, which
are nephrotoxic. Arterial Spin Labelling (ASL) allows
for the assessment renal perfusion without contrast
agent injection. Furthermore ASL offers quantification
of renal blood flow (RBF) which may be a useful imaging
biomarker. This work aims to assess repeatability of
pseudo-continuous ASL1 (pCASL) in healthy volunteers.
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