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Abstract #2194

Renal Perfusion Imaging with Pseudo-continuous Arterial-Spin Labelling (pCASL) at 3.0T: Repeatability in Healthy volunteers.

Magdalena Sokolska 1 , David Thomas 2 , Alan Bainbridge 1 , Xavier Golay 2 , Stuart Taylor 3 , Shonit Punwani 3 , and Douglas Pendse 3

1 UCH Medical Physics and Bioengineering, London, London, United Kingdom, 2 UCL Institute of Neurology, London, London, United Kingdom, 3 Centre for Medical Imaging, UCL, London, United Kingdom

Renal diseases are associated with abnormalities in renal perfusion. Furthermore, characterisation of focal renal lesions such as carcinomas is dependent on the assessment of renal vascularity. Traditionally renal perfusion imaging has relied on contrast agents, which are nephrotoxic. Arterial Spin Labelling (ASL) allows for the assessment renal perfusion without contrast agent injection. Furthermore ASL offers quantification of renal blood flow (RBF) which may be a useful imaging biomarker. This work aims to assess repeatability of pseudo-continuous ASL1 (pCASL) in healthy volunteers.

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