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Abstract #2228

High resolution MRI of the mouse mammary gland

Thomas Neuberger 1,2 , Sooyeon Lee 3 , Gangchea Lee 2 , and Shannon Kelleher 3

1 Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, United States, 2 Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, United States, 3 Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, United States

Female breasts undergo massive changes to transition from a rudimentary structure into a milk secreting organ and back to the pre-pregnant state. We studied the feasibility of imaging the phenotypic changes within mouse mammary glands using high field MRI. The results will assist in developing tools to utilize mouse models in better understanding breast development and disease in women.

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