Abstract #2255
Reduction of cardiac motion-related effects on liver diffusion imaging
Diego Hernando 1 , Utaroh Motosugi 1,2 , Peter Bannas 1,3 , Samir D. Sharma 1 , and Scott B. Reeder 1,4
1
Radiology, University of Wisconsin-Madison,
Madison, WI, United States,
2
Radiology,
University of Yamanashi, Yamanashi, Japan,
3
Radiology,
University Hospital Hamburg-Eppendorf, Hamburg, Germany,
4
Medicine,
University of Wisconsin-Madison, Madison, WI, United
States
Cardiac motion-related effects are severe in liver
diffusion MRI, where they introduce signal voids in
diffusion-weighted images (particularly in the left
liver lobe) and result in errors and high variability in
ADC measurements. This variability has precluded the
widespread application of quantitative liver diffusion
MRI. In this work, we characterize cardiac motion
effects on liver diffusion imaging, and assess simple
correction techniques to reduce variability in ADC maps
by taking maximum intensity over multiple signal
acquisitions (ADCMIP), in which we hypothesized we could
exclude signals affected by cardiac motion. The ADCMIP
was less affected by cardiac-motion than conventional
ADC maps.
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