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Abstract #2297

Improving Image Quality of Hyperpolarized 129Xe MRI with 3D Radial Acquisition and Accurate K-Space Trajectory Measurements

Scott H Robertson 1,2 , Suryanarayanan S Kaushik 1,3 , Zackary L Cleveland 1,4 , Mu He 1 , Matthew S Freeman 1,2 , Rohan S Virgincar 1,3 , and Bastiaan Driehuys 1,4

1 Center for In Vivo Microscopy, Duke University Medical Center, Durham, NC, United States, 2 Medical Physics Graduate Program, Duke University, Durham, NC, United States, 3 Department of Biomedical Engineering, Duke University, Durham, NC, United States, 4 Department of Radiology, Duke University Medical Center, Durham, NC, United States

The 3D Radial sequence has many advantages over 2D multislice GRE, namely isotropic resolution, insensitivity to diffusion, reduced signal decay effects, and the potential for very short echo times. Despite these advantages, however, 2D multislice GRE has remained the preferred sequence for hyperpolarized lung imaging. This study applies a k-space trajectory measurement technique to a 3D radial sequence, making the 3D radial image quality comparable to that of 2D multislice GRE.

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