Abstract #2314
Novel intervention for acute migraine headache investigated by BOLD fMRI
Tie-Qiang Li 1 , Yanlu Wang 1 , Rolf Hallin 2 , and Jan-Erik Juto 3
1
Department of Medical Physics, Karolinska
University Hospital, Huddinge, Stockholm, Sweden,
2
Department
of Neurophysiology, Karolinska University Hospital,
Huddinge, Stockholm, Sweden,
3
Department
of CLINTEC, Karolinska Institute, Huddinge, Stockholm,
Sweden
The purpose of the study was to investigate the
dynamical functional response in hypothalamus to a novel
therapeutic intervention which has been shown to be
extraordinarily effective for treating migraine headache
and narcolepsy. BOLD fMRI experiments were carried out
under a non-invasive intervention for clinical patients
with acute migraine headache attack. The BOLD responses
under different interventional conditions indicate that
restoring the physiological homeostasis in hypothalamus
and associated functional network at the basal of the
brain, which is the control center of the autonomic
nervous system (ANS), provides an efficient approach for
the treatment of central nervous system disorders.
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