Whole-Heart Myocardial BOLD MRI with Adenosine Stress Using Fast Free-Breathing 3D T2 Mapping: A Validation Study in Canines
Hsin-Jung yang 1 , Richard Tang 1 , Avinash Kali 1 , Ivan Cokic 1 , and Rohan Dharmakumar 1
Cedars Sinai Medical Center, Los Angeles,
California, United States
Myocardial BOLD MRI is an emerging non-contrast approach
in the assessment of ischemic heart disease. Most
commonly used myocardial BOLD MR approaches utilized
weighted imaging (T2-weighted, T2*-weighted or bSSFP).
In spite the benefits these techniques have provided to
the advancement of myocardial BOLD imaging, several
limitations continue to persist.. Recently, we developed
a fast, free breathing 3D T2 mapping technique that
utilizes 100% imaging efficiency, which allows for full
coverage of the whole left ventricle within 5 minutes.
In this study, we demonstrate the practical utility of
the approach using a canine model subjected adenosine
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