Meeting Banner
Abstract #2419

Magnetic resonance imaging assessment of excess cardiac iron in thalassemia major: when to initiate?

Xiaodong Chen 1,2 , Zuoquan Zhang 3 , Jinglian Zhong 4 , Qihua Yang 4 , Ziliang Cheng 4 , and Biling Liang 4

1 Sun Yat-Sen Memorial Hospital, Guang Zhou, Guang Dong, China, 2 Guangdong Medical College, Guangdong, China, 3 The Fifth Affiliated Hospital of Sun Yat-Sen University, Guangdong, China, 4 Sun Yat-Sen Memorial Hospital, Guangdong, China

To study the optimal initial age of cardiac iron screening with MRI T2* in patients with thalassemia major(TM). We retrospectively reviewed of cardiac T2* assessments from 102 TM patients between the ages of 3 to 32 years. We found that no patient under 5 years old showed detectable cardiac iron. Cardiac iron level correlated weakly with ferritin and liver iron, but not with patient age. So we drew a conclusion that cardiac iron overload can occur in young patients and assessment of cardiac iron with MRI should be initiated as early as 5 years of age, even in asymptomatic patients.

This abstract and the presentation materials are available to members only; a login is required.

Join Here