Abstract #2478
Comparison of phase-contrast MRI and arterial tonometry pulse wave velocity quantification in young and old healthy subjects
Erin K Englund 1 , Zachary B Rodgers 1 , Prithvi Shiva Kumar 2 , Michael C Langham 3 , Julio A Chirinos 2 , Raymond R Townsend 2 , and Felix W Wehrli 3
1
Department of Bioengineering, University of
Pennsylvania, Philadelphia, PA, United States,
2
Department
of Medicine, University of Pennsylvania, Philadelphia,
PA, United States,
3
Department
of Radiology, University of Pennsylvania, Philadelphia,
PA, United States
Pulse wave velocity (PWV) is the speed at which the
systolic wave front travels in an artery, and provides a
measure of arterial stiffness. While arterial tonometry
is a simple method to quantify central artery PWV, it
cannot assess PWV in specific segments. MRI measurement
of non-gated velocity-encoded projections can provide
vessel-specific quantification of PWV in the carotid
arteries, aortic arch, descending aorta, and iliofemoral
arteries. A full-body segmental MRI PWV protocol was
evaluated nine young and nine old healthy subjects
compared to arterial tonometry. MRI and
tonometry-derived results show that PWV increases with
age in each arterial segment.
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