Blood flow velocity and pulsatility analysis of cerebral small perforating arteries with 7 Tesla quantitative flow MRI.
Willem Bouvy 1 , Geert Jan Biessels 2 , Jaap Kappelle 2 , Peter R Luijten 3 , and Jaco Zwanenburg 3
Brain Center Rudolf Magnus, Department of
Neurology, Utrecht University Medical Centre, Utrecht,
Center Rudolf Magnus, Department of Neurology, Utrecht
University Medical Centre, Utrecht, Netherlands,
of Radiology, Utrecht University Medical Centre,
Aim: To measure blood flow velocity and pulsatility in
small perforating arteries in the cerebral white matter
with 7 Tesla Qflow MRI. Method: Six volunteers aged
18-30 were scanned, and twelve perforating arteries were
analyzed. Results: Flow was pulsatile in all arteries,
with a mean velocity of 0.9cm/s (range 0.23-2.01), and
mean pulsatility index of 0.51(range 0.29-0.83).
Conclusion: Velocity pulsations in small arteries in the
white matter can be directly measured in humans with 7
Tesla Qflow MRI. Partial volume effects and the
direction of flow measurement may have affected our
results, and further validation of this method is
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