High-resolution multi-parametric characterization of atherosclerotic lesions with 3T intravascular MRI
Guan Wang 1,2 , M. Arcan Erturk 1,2 , Shashank Sathyanarayana Hegde 2 , and Paul A. Bottomley 1,2
Electrical & Computer Engineering, Johns
Hopkins University, Baltimore, MD, United States,
H. Morgan Dept. of Radiology & Radiological Sciences,
Johns Hopkins University, Baltimore, MD, United States
The ability to characterize atheroma components is
central to assessing the status of vessel disease, and
its progression and response to intervention. High-field
intravascular MRI (IVMRI) offers the potential for
, proton density
and lipid burden in healthy and diseased vessels at a
resolution approaching 100m. Here, results from
multi-parametric, 200m-resolution intravascular IVMRI
employing a novel Tri-Flip-Angle method are presented.
proton density are mapped with B
in only four acquisitions, while the lipid pool is
imaged by Dixon (or selective saturation) techniques in
human iliac artery specimens.
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