31P DWS of different muscles in the lower leg
Melissa Hooijmans 1 , Ece Ercan 1 , Robert Brandt 1 , Andrew Webb 1 , Hermien Kan 1 , and Itamar Ronen 1
Radiology, Leiden University Medical Center,
Leiden, Zuid-holland, Netherlands
Conventional diffusion weighted imaging is limited by
the lack of compartment specificity of water. In this
work, we show the application of 31P diffusion weighted
spectroscopy of individual muscles in the lower leg at
7T. SNR was sufficient to determine apparent diffusion
coefficients of phosphocreatine (PCr) in two different
muscles of the leg. In conclusion we are able to assess
the diffusion of PCr in the individual lower leg muscles
and these values seem to be affected more by cell size
than fiber type distribution.
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