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Abstract #2726

Selective ASL delineates borderzone territories in patients with stenosis of the middle cerebral artery

Andrea Federspiel 1 , Mirjam Rachel Heldner 2 , Urs Fischer 2 , Jan Gralla 3 , and Roland Wiest 3

1 Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bern, Bern, Switzerland, 2 Department of Neurology and Stroke Center, University of Bern, Bern, Bern, Switzerland, 3 Institute of Diagnostic and Interventional Neuroradiology, University of Bern, Bern, Bern, Switzerland

In the present study the relationship between cerebral blood flow (CBF) and CBF velocity was investigated in a cohort of twenty patients with intracranial stenosis. After rigorous treatment physiology-related artefacts of vessel-selective arterial spin labeling (sASL) time series a significant positive linear relationship located within the anterior and posterior watershed areas of the middle cerebral artery (MCA). The findings of the present study suggest that regional CBF measures along watershed territories as measured by sASL are reliable markers of sufficient collateral supply.

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