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Abstract #2761

Overhauser-enhanced MRI with SENSE Acceleration in the Johnson Noise Dominated Regime

Cristen D LaPierre 1 , Mathieu Sarracanie 1,2 , Brandon Dean Armstrong 1,2 , Jonathan R Polimeni 1,3 , and Matthew S Rosen 1,2

1 Department of Radiology, A.A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 2 Department of Physics, Harvard University, Cambridge, MA, United States, 3 Harvard Medical School, Boston, MA, United States

Low SNR and long acquisition times are the primary hindrance to deployable low-field MRI scanners. .Due to low Boltzmann polarization, enhancement techniques such as Dynamic Nuclear Polarization (DNP) and image acceleration techniques like SENSitivity Encoding (SENSE) will be vital to obtaining high quality images in reasonable times. In this study an eight-coil receive-only array for 6.5 mT was used with a 14 cm saddle coil and 30 cm NMR Transmit coil to acquire DNP + SENSE images of a structured phantom. Future work will improve SENSE reconstruction as well as compare it to incoherent random undersampling strategies.

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