Analysis of proton MRSI metabolites with improved tissue segmentation at 7T
Yoojin Lee 1 , Tae Kim 1 , Tiejun Zhao 2 , Jullie W. Pan 1 , and Hoby P. Hetherington 1
Department of Radiology, University of
Pittsburgh, Pittsburgh, Pennsylvania, United States,
Medical Solution USA, INC., Siemens MediCare USA,
Pittsburgh, Pennsylvania, United States
In this study, we use B1 inhomogeneity correction method
in MPRAGE image to improve tissue segmentation at 7T and
apply this accurate segmentation result for more precise
metabolic analysis for MRSI. The data set of percent GM
from segmentation results and Cr/NAA from MRSI data was
used for linear regression analysis. The patient data
was also acquired and compared with the linear
regression result of normal subject data.
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